Ménétrier's disease is classified as a hyperplastic gastropathy, also known as giant hypertrophic gastritis. Endoscopically, the gastric body exhibits enlarged, thickened, and convoluted folds resembling cerebral gyri, while the gastric antrum mucosa is often normal. Increased gastric mucus secretion leads to significant protein loss through gastric fluid, frequently resulting in hypoproteinemia. This condition is more common in males, and its etiology remains unknown. When diagnosing this disease, it is important to exclude malignant infiltration of the gastric mucosa and lymphoma. There is no specific treatment for Ménétrier's disease, and it carries a certain risk of malignant transformation.