Fatty liver disease (FLD), also referred to as metabolic dysfunction-associated fatty liver disease (MAFLD) or metabolic dysfunction-associated steatotic liver disease (MASLD), is a clinical and pathological syndrome characterized by excessive accumulation of fat and steatosis in hepatocytes. Risk factors for FLD include obesity, alcohol consumption, diabetes, malnutrition, certain medications, pregnancy, and infections. Based on histological features, FLD is classified into fatty liver and steatohepatitis. Additionally, depending on the etiology and the presence or absence of long-term excessive alcohol consumption, FLD is further divided into non-alcoholic fatty liver disease (NAFLD) and alcoholic fatty liver disease (AFLD).
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